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KMID : 0882420130850010067
Korean Journal of Medicine
2013 Volume.85 No. 1 p.67 ~ p.72
A Case of Hemolytic Uremic Syndrome after Transarterial Chemoembolization with Cisplatin
Yang Jee-Eun

Kim Kang-Mo
Shim Ju-Hyun
Lim Young-Suk
Lee Han-Chu
Chung Young-Hwa
Lee Yung-Sang
Abstract
Hemolytic uremic syndrome (HUS) is a rare disorder characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. These characteristics are related to the formation of platelet-rich microthrombi in the microvasculature. HUS is associated with a variety of etiologies, including cisplatin. Previously reported HUS cases after cisplatin administration were almost always related to systemic combination chemotherapy that included cisplatin. Transarterial chemoembolization (TACE) is commonly used in treatment of hepatocellular carcinoma, and most centers in Korea use cisplatin. A 70-year-old female with hepatocellular carcinoma was treated with TACE including cisplatin and subsequently developed clinical and laboratory findings compatible with HUS.
KEYWORD
Hemolytic uremic syndrome, Chemoembolization, Therapeutic, Cisplatin
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